Stem Cells: From Cancer Vaccines to Space Research Artwork

The Stem Cell Report with Martin Pera

Stem cell science has catapulted to the forefront of biomedical research over the last decade, bringing with it the potential to transform human health and the treatment of devastating diseases and disorders. Martin Pera, an internationally recognized stem cell pioneer and the dynamic editor-in-chief of Stem Cell Reports, explores basic discoveries in stem cell research and its application. Dr. Pera goes “beyond the paper,” bringing authors together to draw new insights and explore the questions and creativity that drive new breakthroughs. Stem Cell Reports, published by the International Society for Stem Cell Research (ISSCR), is an open-access, peer reviewed journal that supports the field of stem cell research and regenerative medicine.

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The Stem Cell Report with Martin Pera

Stem Cells: From Cancer Vaccines to Space Research

June 07, 2021 • Season 1 • Episode 3

In today’s episode, we will talk about new research on the use of an induced pluripotent stem cell-based vaccine to potentially protect against pancreatic cancer. This approach takes advantage of shared antigens between stem cells and pancreatic cancer cells and seeks to exploit them for clinical benefit. We will talk with the authors of this new research published in Stem Cell Reports on why they decided to pursue this approach, the background behind it, and whether this approach could work for other types of cancers. We also discuss some of Dr. Wu's other work, including research on stem cells in microgravity.

Show Notes

Guests
Joseph Wu, MD, PhD Director of the Stanford Cardiovascular Institute, US
Website: http://med.stanford.edu/wulab.html

Xiaoming Ouyang, PhD, Postdoctoral Scholar, Wu Laboratory, Stanford University, US
Website: https://www.researchgate.net/profile/Xiaoming-Ouyang

Host
Martin Pera, PhD – Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory
Website: https://www.jax.org/research-and-faculty/faculty/martin-pera
Twitter: @martinperaJAX

Supporting Documents
Anti-Tumor Effects of iPSC-Based Cancer Vaccine in Pancreatic Cancer
https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(21)00199-5

About Stem Cell Reports
Stem Cell Reports is the Open Access journal of the International Society for Stem Cell Research for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.
Twitter: @stemcellreports

About ISSCR
With nearly 4,000 members from more than 65 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.
Twitter: @ISSCR

Acknowledgements
ISSCR Staff
Keith Alm, Chief Operating Officer
Bethany Almon, Senior Manager of Integrated Marketing
Yvonne Fisher, Managing Editor, Stem Cell Reports
Kym Kilbourne, Director of Media and Strategic Communications
Jack Mosher, Senior Manager of Scientific Affairs
Nancy Witty, Chief Executive Officer

Voice Work
Julie Perlin
Ben Snitkoff

Music
@Konovalov