Transcription Factor Dance Party - Building Dopaminergic Neurons Artwork

The Stem Cell Report with Martin Pera

Stem cell science has catapulted to the forefront of biomedical research over the last decade, bringing with it the potential to transform human health and the treatment of devastating diseases and disorders. Martin Pera, an internationally recognized stem cell pioneer and the dynamic editor-in-chief of Stem Cell Reports, explores basic discoveries in stem cell research and its application. Dr. Pera goes “beyond the paper,” bringing authors together to draw new insights and explore the questions and creativity that drive new breakthroughs. Stem Cell Reports, published by the International Society for Stem Cell Research (ISSCR), is an open-access, peer reviewed journal that supports the field of stem cell research and regenerative medicine.

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The Stem Cell Report with Martin Pera

Transcription Factor Dance Party - Building Dopaminergic Neurons

August 09, 2021 • Season 1 • Episode 5

In this episode, sponsored by bit.bio, Drs. Marius Wernig and Yi Han Ng join the podcast to talk about the directed differentiation of pluripotent stem cells into dopaminergic neurons. Their approach, which is based on the expression of specific transcription factors to drive cell fate directly to a specific neuronal identity, has been demonstrated to robust generalate functional dopaminergic neurons of midbrain character.

Guests
Marius Wernig, MD, PhD, Associate Professor of Pathology at the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University
Website: https://www.werniglab.org/

Yi Han Ng, PhD, Institute for Stem Cell Biology and Regenerative Medicine and Department of Pathology, Stanford University School of Medicine and Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, Agency for Science, Technology and Research, Singapore

Supporting Documents
Efficient Generation of Dopaminergic Induced Neuronal Cells with Midbrain Characteristics

Host
Martin Pera, PhD: Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory
Twitter: @martinperaJAX

About Stem Cell Reports
Stem Cell Reports is the open access journal of the International Society for Stem Cell Research for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.
Twitter: @StemCellReports

About ISSCR
With nearly 4,000 members from more than 65 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.
Twitter: @ISSCR

Acknowledgements

ISSCR Staff
Keith Alm, Chief Executive Officer
Bethany Almon, Senior Manager of Integrated Marketing
Yvonne Fisher, Managing Editor, Stem Cell Reports
Kym Kilbourne, Director of Media and Strategic Communications
Jack Mosher, Senior Manager of Scientific Affairs

Voice Work
Julie Perlin
Ben Snitkoff

Music
@Konovalov