The Satellite View: Muscle Stem Cells and Muscle Disease

Over the last 10 years of Stem Cell Reports, the journal has published nearly 2,000 papers across the breadth of stem cell research. In this special episode of the podcast, we are celebrating the anniversary of the journal by talking with the authors from some of the most highly cited publications in the journal's history.

The guests on this episode of the podcast have collective expertise that makes them the “dream team” of muscle stem cell biology and its application to treat disease.  

 Akitsu Hotta is a Principal Investigator and Associate Professor in the Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University and was the recipient of the 2020 Japanese Society for Regenerative Medicine Award. His laboratory published the 2015 paper, Precise correction of the dystrophin gene in Duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9. 

Thomas Rando is the Director of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Biology at the University of California Los Angeles, where he is also Professor of Neurology and of Molecular, Cell and Developmental Biology. Dr Rando is a board-certified neurologist and a member of the National Academy of Medicine and a member of the American Academy of Arts and Sciences. He is also the 2023 recipient of the ISSCR Achievement Award, which recognizes the transformative body of work of an investigator that has had a major impact on the field of stem cell research or regenerative medicine. His laboratory published the 2015 paper, entitled, the Ex vivo expansion and in vivo self-renewal of human muscle stem cells. 

April Pyle is an Associate Professor in the Department of Microbiology, Immunology and Molecular Genetics at the University of California Los Angeles and a member of the Eli and Edythe Broad Stem Cell Center, the Center for Duchenne Muscular Dystrophy, and the Jonsson Comprehensive Cancer Center at UCLA. She is also an Associate Editor of Stem Cell Reports.

Host
Martin Pera, PhD, Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory
Twitter: @martinperaJAX

About ISSCR
With more than 4,600 members from 75+ countries, the International Society for Stem Cell Research (@ISSCR) is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.

ISSCR Staff
Keith Alm, Chief Executive Officer
Yvonne Fisher, Managing Editor, Stem Cell Reports
Kym Kilbourne, Director of Media and Strategic Communications
Jack Mosher, Scientific Advisor

Voice Work
Ben Snitkoff